▷ Best Supplements for Chronic Fatigue (2024 Update)

Best Supplements for Chronic Fatigue

Best Energy Supplements for Chronic Fatigue

Chronic fatigue syndrome is a chronic illness (as its name suggests) that is typified by extremely low energy levels in conjunction with constant – and debilitating – fatigue.

Interestingly, when it comes to chronic fatigue, there does not appear to be any definite underlying cause. As a result, it can be exceedingly challenging to treat, with a cure being non-existent at this point in time.

It is important to note that although a specific treatment is yet to be determined, there have been a number of things that are thought to contribute to its onset.

The accumulation of excessive physical, emotional, and mental stress, have been shown to lead to a huge increase in systemic inflammation. This can result in the body being placed under an excessive amount of metabolic stress, resulting in a drop in energy levels and an associated decline in hormonal and physical function.

Similarly, a poor diet has also been thought to increase the likelihood of developing chronic fatigue syndrome.

You see, the body requires a vast amount of essential nutrients to survive and function optimally each and every day. If our diet is lacking in these nutrients, we can see an associated drop in function combined with a large and rapid increase in fatigue.

And finally, there are also preliminary finding suggesting that those individuals who suffer from chronic fatigue will also present with hormonal dysfunction – which can certainly contribute to an inability to produce energy on a consistent basis.

Taking this into consideration, supplements do certainly have their place when it comes to increasing energy levels, maintaining optimal hormone function, and improving upon the state of chronic fatigue syndrome [1].

What Does a Chronic Fatigue Energy Supplement Do?

As previously mentioned, two of the biggest factors that are thought to contribute to chronic fatigue syndrome are nutritional deficiency and hormone imbalances.

With this in mind, an energy supplement specifically designed with chronic fatigue syndrome in mind needs to fill those gaps. This means that they should provide us with a way to increase our intake of those nutrients essential to maintaining optimal function, while also including ingredients that can restore the balance of the hormonal system.

It is important to note the these supplements are just that – supplements – and as such should be used in conjunction with other recovery strategies to improve the state of chronic fatigue and boost energy levels.

This makes them the perfect addition to rest, exercise therapy, a good quality sleep routine, and various other relaxation techniques.

What to Look for in an Energy Supplement?

While we certainly want to ensure that all our basis are covered in terms of nutrient intake, there are a number of key ingredients that have been shown to have significant benefit when it comes to boosting energy levels and improving hormone function specifically.

These key compounds include:

  • Vitamin B6: is a key vitamin found in wild fish, such as tuna and salmon, grass fed beef, spinach, and hazelnuts (which probably explains why the vast majority of the population is deficient in it…). The supplementation of Vitamin B6 has been shown to relieve fatigue, increase energy, and support the immune system, suggesting its benefit in boosting energy in those suffering from chronic fatigue [2].
  • Vitamin B12: is a specific nutrient that has been shown to have a strong impact on our energy levels. With this in mind, those who are vitamin B12 deficient have been shown to have low energy and motivation, inhibited focus, poor memory, and mood swings. Conversely, the supplementation of Vitamin B12 has been shown to reverse these effects, boosting energy production and increasing mood [1].
  • Magnesium: is a mineral that plays an important role in both hormone and energy production. As such, the supplementation of magnesium in chronic fatigue patients has been shown to improve energy level, reduce stress, and balance emotional state, suggesting its importance [3].

Now, it is important to again note that our best options when it comes to increasing energy levels and dealing with the negative impacts of chronic fatigue is to increase our nutrient intake in all aspects.

With this in mind a good quality multivitamin is our best option – assuming that it includes the three key ingredients above, of course.

Best Energy Supplement for Chronic Fatigue Review

As with all things, some supplements are much better than others.

The three options outlined below are what we believe to be the best available on the market today. Not only do they provide the body with a host of essential vitamins and minerals, they also include a large dose of Vitamin B6, Vitamin B12, and Magnesium, making them excellent options.

This Dr Tobias multivitamin is one of the most popular on the market – and for very good reason too. Not only does it tick all the required boxes in terms of essential nutrients, but it offers enhanced bioavailability. This means that it is absorbed more readily into the blood stream than some lower quality options.

Despite being more of a performance based supplement brand, MuscleTech are well regarded for producing high quality products that you can trust completely – and their multivitamin is absolutely no different.

Containing a full array of essential minerals in high doses, it is a fantastic option of those looking to boost energy levels and fight fatigue safely and efficiently.

Centrum are arguably the most well-known multivitamin producers in existence. Their products are of a high quality, contain all relevant vitamins and minerals, and are completely non-GMO and gluten free.

This makes them a perfect options for literally anyone looking to increase their nutrient intake and boost energy.


Despite not having a clear cause or cure, supplements do offer a way to help in the management of chronic fatigue. With this in mind, they have the capacity to ensure the body has adequate nutrients available to maintain optimal energy production and hormone function.

The three options outlines in this article are each great choices in their own right. With this in mind, if you have had any experience with them we would love to hear about it – so drop us a comment and we will get back to you ASAP.


About the author

Sabrina Wilson

Sabrina Wilson is an author and homemaker who is passionate about a holistic approach to health. When she is not writing she can be found tooling around in her garden with the help of her appropriately named dog Digby, bicycling in the park, and occasionally rock climbing…badly. Sabrina is a staff writer for the Organic Daily Post.

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